Is G-CSF safe?

In the beginning of 2011, the Journal of Blood Society published a paper on the safety of G-CSF administration. The number of subjects who participated in the experiments neared 4000. After 12 years follow up, the subjects displayed no side effects and adverse event. The article was published in January, 2011.

Another G-CSF follow up study is conducted in 2013. According to the results, the vast majority of PBSC donors consider their general condition excellent or good throughout the observation period.

For reference, please refer to: http://bloodjournal.hematologylibrary. & https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776391/