[News] Are you tired? Stem cells can improve the root cause of "Chronic Fatigue Syndrome"

Are you tired? Stem cells can improve the root cause of "Chronic Fatigue Syndrome" 2022-6-27  "Recently, I can't get enough sleep, and I'm still very tired when I wake up.”; "my memory becomes poor, I can't concentrate, and often have brain fog"; " painful joints and muscles in many different places, very distu...more

[Media] [We People] Breakthrough for cell therapies

Breakthrough for cell therapiesWe People Magazine 2022年 Spring No.180 P.60~63 (Click the photos to read...) ...more

Q:What is the difference between PBSC (autologous peripheral blood bone marrow stem cells) & Immune Cells & MSC (mesenchymal stem cells)?

[PBSC - Autologous peripheral blood bone marrow stem cells] can form a microenvironment in the body, allowing the stem cell population to carry out all-round regeneration and repair of the body. PBSC contains many different types of stem cells, mainly HSC (hematopoietic stem cells), also a small portion of  MSC (mesenchymal stem cells), hematopoietic precursor cells, endothelial precursor cells, and micro-embryonic stem cells. In the proc......more

Q:Why store peripheral stem cells?

There are about 60 trillion cells in the body, about 60-1200 billion cells die every day, and about the same number of cells differentiated by stem cells at the same time. When the rate of cell death is faster than cell regeneration, people age. Their immune system is down and diseases begin to surface. While people are aging, stem cells are also aging, and the ability to regenerate and repair is deteriorating. Therefore, storing healthy ......more

Q:Can I use my child’s umbilical cord blood as a source of younger stem cells?

Umbilical cord blood must be collected immediately upon birth. While there are hematopoietic stem cells and mesenchymal stem cells in the cord blood, the numbers thereof are limited. Furthermore, for average adult to make practical use of the cord blood stem cells, there must be sufficient amount of the stem cells. If this is the case, pairing is required. Often, the pairing process fails due to issues of repellence. If not for sever......more

Q:What is G-CSF?

G-CSF (Granulocyte colony Stimulating Factor) is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Beside the effect on the hematopoietic system, G-CSF can also act on neuronal cells as a neurotrophic factor. The action of G-CSF in the central nervous system is to induce neurogenesis, to increase the neuroplasticity and to counteract apoptosis. G-CSF is als......more

Q:Why inject G-CSF?

After the injection of G-CSF, several different cells, including but not limited to, HSCs, MSCs, B-cell, T-Cell Lymphoma, will be stimulated and released into the bloodstream. The amount of stem cells stimulated and released into the bloodstream will vary depending on the conditions of each individual. It is possible for the amount to increase ten- or even hundredfold. Using the technique for collecting peripheral blood bone marrow s......more

Q:Is G-CSF safe?

In the beginning of 2011, the Journal of Blood Society published a paper on the safety of G-CSF administration. The number of subjects who participated in the experiments neared 4000. After 12 years follow up, the subjects displayed no side effects and adverse event. The article was published in January, 2011. Another G-CSF follow up study is conducted in 2013. According to the results, the vast majority of PBSC donors consider t......more

Q:Besides infectious diseases and coagulant diseases, what other conditions or circumstances would make an individual inapt to collect peripheral blood stem cells?

■ Individuals with chronic Myelogenous Leukemia or Aplastic Amenia, or individuals undergoing chemotherapy. ■ Pregnant women, and women in the process of breast-milk feeding. ■ Individuals with Deep Vein Thrombosis or Pulmonary Thrombo-Embolic disease. ■ Individuals with mental diseases or individuals on drugs containing Lithium. ■ Individuals who take antibiotics to reduce inflammations. If an ......more

Q:What is the age limit for peripheral blood stem cells collection?

As long as you are above twenty years old and maintain a rather healthy condition, you are eligible to have your peripheral blood stem cells collected. There is no upper age limit for the collection. However, as you age, both the number of your stem cells and the quality (repopulating ability) of which may decrease. As a result, we advise that you put in reserve your stem cells as early as possible.  ...more

Q:What’s the best interval between multiple PBSC collection?

The common standard in the U.S. today is to wait three months for the next collection. To ensure efficient collection, we would recommend next harvesting must begin when your physical and mental states restore to their ideal levels. Thus, at least one year after prior mobilization is recommended. ...more

Q:Could I collect my peripheral blood stem cells when I’m sick?

For certain diseases or illnesses, the individual could still collect his or her stem cells after proper treatment. However, ailments or medications may have affected stem cells counts. It is possible that such negative impact may cause the body to response poorly to G-CSF injection. If poor mobilization happens, the number of stem cells collected are not adequate for practical use. Therefore, it is better to preserve your stem cel......more

Q:Where does Enhance Cell Bank store my stem cells?

We store your stem cells in our state-of-the-art processing and storage lab “The NHRI Cell Bank.” We use a class 100,000 clean room to minimize viable and nonviable particle counts. Designed for efficiency and sterility, the lab equipped with the same freezers used by major research institutions. The quality management system also achieved ISO 9001, showing our commitment to our quality and service. ...more

Q:Why store stem cells in multiple compartments?

In order to preserve the flexibility for different therapeutic use, we would sort your stem cells, depending on the number and density thereof, into cryo tubes and reserve them accordingly....more

Q:How would Enhance Cells Bank perform the quality control in order to eliminate any foreseeable risks?

Our lab specialists inspect and monitor every step of the process with discretion. The entire process follows high GTP (Good Tissue Practice) Laboratory standards in a dust-free environment. To ensure the purity and safety of the stem cells, it’s necessary to design and implement a comprehensive testing program. Sterility testing ensures that the cells are free from bacteria, fungi, and mold, which can be introduced through cont......more

Q:How long can stem cells be stored ?

Once processing is complete, our lab specialists transfer your stem cells to cryo tubes for cryopreservation. The cryo tubes are then frozen and stored at or below -196 degrees Celsius, where biological activity ceases. Scientists believe that if stem cells are properly stored and processed, they should last indefinitely. Therefore, your stem cells remain viable for therapeutic use when thawed. ...more

Q:How does Enhance Cell Bank preserve the vitality of stem cells?

A key to preserve both viability and functionality of stem cells requires very dedicated efforts. Enhance Cell Bank specifically developed a rapid and efficient process to eliminate any potential damage to stem cells. This process results in highest stem cells survival rate. A temperature-controlled cryopreservation instrument is used to freeze stem cells to prevent any ice crystal formation during the freezing process. Subsequentl......more